01:16 , Feb 27, 2018 |  BC Extra  |  Preclinical News

Mutant p53 promotes tumor growth via exosomal miR-1246

A new study from the National Institutes of Health suggests mutant p53 promotes cancer progression by creating an immunosuppressive tumor microenvironment, in addition to its known roles inside cancer cells. p53 is one of the...
07:00 , Jul 21, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: MicroRNA-1246 (miR-1246); miR-1290

Cancer INDICATION: Non-small cell lung cancer (NSCLC) Patient sample, cell culture and mouse studies suggest inhibiting miR-1246 or miR-1290 could help treat NSCLC. In lung tissue samples from NSCLC patients, levels of miR-1246 and miR-1290...