BioCentury | Sep 1, 2016
Distillery Therapeutics

Therapeutics: Mex-3 RNA binding family member B (MEX3B); interleukin-33 (IL-33; NF-HEV); granulocyte macrophage colony-stimulating factor (GM-CSF; CSF2)

Inflammation INDICATION: Asthma Cell culture and mouse studies suggest inhibiting MEX3B could help treat asthma. In a mouse respiratory epithelial cell line, siRNA or locked nucleic acid (LNA) targeting MEX3B decreased expression of the T...
BioCentury | Mar 7, 2013
Distillery Therapeutics

Indication: Cancer

...status Publication and contact information Cancer Solid tumors Phosphatidylinositol glycan anchor biosynthesis class N (PIGN); mex-3 homolog C (MEX3C)...
...solid tumors. In 26 colorectal tumor samples and 20 cell lines showing chromosomal instability, PIGN, MEX3C...
...instability and were frequently deleted in tumors. In a colorectal cancer cell line lacking PIGN, MEX3C...
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