BioCentury | Jul 3, 2020
Translation in Brief

Tesla developing RNA therapeutic ‘microfactories’ for CureVac, plus CRISPR-directed RNA epigenetic modifications and Nucleix

...3 METTL14 - Methyltransferase like 14 BioCentury Staff Bladder EpiCheck CureVac AG Broad Institute of MIT and Harvard Nucleix Ltd. CRISPR-associated protein 13b (Cas13b) Methyltransferase like 14 (METTL14) Methyltransferase...
BioCentury | Jun 5, 2020
Deals

AstraZeneca adds RNA-modifying targets to oncology pipeline via Accent deal

...Therapeutics Ltd., which has a METTL3 inhibitor; and Gotham Therapeutics Corp., which is targeting the METTL3/METTL14...
...regulation. Targets ADAR (ADAR1) - Adenosine deaminase RNA-specific METTL3 - Methyltransferase like 3 METTL14 - Methyltransferase like 14 Sandi...
BioCentury | Sep 20, 2019
Preclinical News

Storm shows PoC for RNA epigenetic inhibitor as field moves toward clinic

...for AML” ). One of Accent’s lead programs also targets METTL3, and Gotham’s targets the METTL3/METTL14...
...hasn’t disclosed specific indications, according to Gotham co-founder and COO Birgit Zech. Targets: METTL14 - Methyltransferase like 14...
BioCentury | Jul 19, 2019
Tools & Techniques

A mark up for RNA epigenetics

...cancer pathogenesis, said Storm CSO Oliver Rausch. Accent’s lead program targets METTL3 and Gotham’s the METTL3/METTL14...
...Chicago, Ill. Weill Cornell Medicine, New York, N.Y. Targets METTL3 - Methyltransferase like 3 METTL14- Methyltransferase like 14 Allison...
BioCentury | Mar 3, 2016
Distillery Therapeutics

Therapeutics: Methyltransferase like 3 (METTL3); METTL14

...Infectious disease INDICATION: HIV / AIDs Cell culture studies suggest inhibiting METTL3 or METTL14 could help...
...help treat HIV / AIDS. In HIV-infected human CD4+ T cells, shRNA targeting METTL3 or METTL14...
...METTL14 inhibition in an animal model of HIV infection. TARGET/MARKER/PATHWAY: Methyltransferase like 3 (METTL3) ; METTL14...
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