BC Innovations | Mar 10, 2016
Targets & Mechanisms

Brown fat heats up

While FGF21 is the clear frontrunner target for stimulating brown and beige fat, players in the seven year-old field believe there's room for plenty more runners in the race. Since the start of the year,...
BC Innovations | Jul 10, 2014
Distillery Therapeutics

Indication: Various

Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Obesity; inflammation Meteorin glial cell differentiation regulator-like (METRNL) Mouse studies suggest increasing METRNL signaling could help treat obesity and inflammatory diseases. In mice, an adenoviral...
BC Innovations | Jul 10, 2014
Cover Story

Going immune on beige fat

Since its founding in 2010, Ember Therapeutics Inc. has been exploiting the biology of brown and beige fat to treat metabolic diseases, including obesity and type 2 diabetes. Now, the biotech has an option to...
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