BioCentury | Dec 21, 2018
Product R&D

Cell therapies seek solid ground

...target MAGEA3 have led to deaths from neurotoxicity based on cross-reactivity with the familial protein MAGEA12...
...leukocyte antigen KRAS (K-Ras) MART1 (MLANA) - Melan-A MAGEA3 - Melanoma-associated antigen A3 MAGEA12 - Melanoma-associated antigen A12...
BioCentury | Aug 29, 2013
Cover Story

Sleuthing for toxicity

...trial in patients with metastatic cancer given an affinity-enhanced TCR targeting three MAGEAs-MAGEA3, MAGEA9 and MAGEA12-resulted...
...samples using real-time quantitative PCR, nanostring quantitation and deep sequencing showed that one of the antigens-MAGEA12-was...
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