BioCentury | Jun 14, 2019
Preclinical News

June 13 Preclinical Quick Takes: A*STAR's mAb against tumor-displayed antigen; plus Columbia, Genentech and more

...of Arkansas team developed Cytophone, a platform that non-invasively detects circulating tumor cells (CTCs) expressing melanin...
BioCentury | Apr 19, 2018
Preclinical News

Synthetic tattoo could detect asymptomatic cancer

...to TYR expression, which in turn synthesizes the black pigment melanin. The resulting accumulation of melanin...
BioCentury | Nov 6, 2014
Distillery Techniques

Technology: Imaging

...Melanin-based nanoparticles could be useful for imaging melanoma tumors in patients. The surfaces of water-soluble melanin...
BioCentury | Oct 24, 2013
Distillery Techniques

Technology: Imaging

...agent derived from a melanin-binding small molecule could be useful for detecting metastatic melanoma tumors. Melanin...
...in melanoma tumors than in normal tissues. In a mouse model of melanoma, an 18F-labeled, melanin-binding...
BioCentury | Nov 15, 2012
Distillery Therapeutics

Indication: Cancer

...UV exposure, than dark-skinned mice with low levels of pheomelanin or albino mice that lacked melanin...
BioCentury | Jun 28, 2012
Strategy

Pharma compounds at the crossroads

...COPD 1 to treat COPD, MS, liver fibrosis Asthma, emphysema, bacterial infection Bristol-Myers Squibb BMS-830216 Melanin-concentrating...
BioCentury | Apr 9, 2012
Regulation

A longer weight

...recruit more than 4,000 high-risk patients in a Phase III program. Albany Molecular is developing melanin-concentrating...
BioCentury | Oct 24, 2011
Clinical News

ALB-127158: Development discontinued

...Albany, N.Y. Product: ALB-127158(a) Business: Endocrine/Metabolic Molecular target: Melanin-concentrating hormone receptor 1 (MCHR1) (GPR24) Description: Melanin-concentrating...
BioCentury | Jun 20, 2011
Clinical News

ALB-127158: Phase I data

...Albany, N.Y. Product: ALB-127158(a) Business: Endocrine Molecular target: Melanin-concentrating hormone receptor 1 (MCHR1) (GPR24) Description: Melanin-concentrating...
BioCentury | Mar 17, 2011
Distillery Techniques

Technology: Imaging

...melanoma. In sections from 42 pigmented skin samples, laser-based imaging to determine the ratio of melanin...
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