07:00 , Oct 30, 2008 |  BC Innovations  |  Distillery Therapeutics

Indication: Endocrine disease

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Endocrine disease Type 2 diabetes Mitogen-activated protein kinase 8 (JNK1; MAPK8); mitogen-activated protein kinase 8 interacting protein 1 (JIP1; MAPK8IP1; IB1)...
07:00 , Oct 30, 2008 |  BC Innovations  |  Targets & Mechanisms

Block JNK at the dock

A team of U.S. researchers has described a new mitogen-activated protein kinase 8 ( JNK ; MAPK8 ) inhibitor that targets JNK's substrate docking site-instead of its ATP binding site-to treat type 2 diabetes. 1...