07:00 , Aug 26, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Malonyl-CoA decarboxylase (MLYCD; MCD); pyruvate dehydrogenase kinase (PDK); 3-ketoacyl-CoA thiolase (ACAA2) A study in mice suggests that inhibiting MCD, PDK or ACAA2 could...
07:00 , Aug 26, 2010 |  BC Innovations  |  Targets & Mechanisms

Metabolic origins for pulmonary hypertension

Researchers at the University of Alberta and Metabolic Modulators Research Ltd. have shown that a pathological shift toward glycolysis could be responsible for the deleterious vascular remodeling seen in pulmonary arterial hypertension. 1 The findings...