20:40 , Feb 23, 2017 |  BC Innovations  |  Translation in Brief

Just the essentials

A team led by University of Texas MD Anderson Cancer Center President Ronald DePinho has developed a method of scouring cancer genome databases for new targets by looking for what he calls "the ghosts of...
02:01 , Feb 23, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Pancreatic cancer Cell culture and mouse studies suggest inhibiting ME3 could help treat SMAD4 -deficient pancreatic ductal adenocarcinoma (PDAC) that is also deficient in the housekeeping gene ME2 . In 185 PDAC genomes in...
08:00 , Jan 31, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer NADP-dependent malic enzyme 1 cytosolic (ME1); NADP-dependent malic enzyme 2 mitochondrial (ME2); p53 Cell culture and mouse studies suggest inhibiting ME1 or ME2 may...