BioCentury | Feb 1, 2019
Tools & Techniques

TMB needs company

...CXC chemokine receptor 6; HLA-DQA1 - Major histocompatibility complex class II DQ alpha 1; HLA-DRB1...
BioCentury | Mar 10, 2016
Tools & Techniques

Ziopharm bets on the HLA-A odds

...HLA-C , and MHCII genes include HLA-DR . The most prevalent form of HLA-DR is HLA-DRB1...
...to obtain a match for seven out of eight alleles of HLA-A, HLA-B, HLA-C and HLA-DRB1...
...a match for six out of six alleles after removal of HLA-A, HLA-B, HLA-C or HLA-DRB1...
BioCentury | Oct 31, 2013
Targets & Mechanisms

Personal factors

...MHCII DR b1 ( HLA-DRB1 ) locus to predict foreign peptides with high affinity for HLA-DRB1...
...induce an immune response. The group found that, as expected, the number of high-affinity foreign peptide-HLA-DRB1...
BioCentury | Jun 7, 2012
Tools & Techniques

HLA in sequence

...HLA-A ), HLA-B , HLA-C and major histocompatibility complex class II DR b1 ( HLA-DRB1...
BioCentury | Oct 29, 2009
Distillery Therapeutics

Indication: Autoimmune disease

...histocompatibility complex class II DQ a1 (HLA-DQA1); HLA-DQB1; major histocompatibility complex class II DR b1 (HLA-DRB1...
...the strongest correlations were between a SNP on HLA-C and myasthenia gravis (p=0.001); SNPs on HLA-DRB1...
BioCentury | Oct 22, 2009
Distillery Techniques

Technology: Markers

...protein (MLXIP) in muscle increased, whereas expression of major histocompatibility complex class II DR b1 (HLA-DRB1...
BioCentury | Aug 7, 2008
Distillery Therapeutics

This Week in Therapeutics

...II, DR-b1 (HLA-DRB1) A genetic analysis of subjects with MS suggests that the HLA-DRB1*0401 and HLA-DRB1*0408...
...of IFN-β therapy in MS. Patients on long-term IFN-β therapy who carried the HLA-DRB1*0401 or HLA-DRB1*0408...
...alleles (p<0.01). Furthermore, antibody neutralizing activity was significantly increased in the sera of HLA-DRB1*-0401- and HLA-DRB1*0408-positive...
BioCentury | Nov 17, 1997
Tools & Techniques

Other RA players speak up

...with cancer and AIDS. ANRG's vaccine is a 20-amino acid peptide based on HLA-DR4 and HLA-DRB1...
...than drugs that are further along in development," said President and CEO Barry Sherman. The HLA-DRB1...
...to avoid potential safety problems such as systemic immunosuppression, patients with two copies of the HLA-DRB1...
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