BioCentury | Dec 8, 2017
Targets & Mechanisms

Epiphenomena at ASH

While it’s no surprise that cell therapy research is dominant in hematology, the emergence of epigenetics as an equally large focus at this year’s ASH meeting is more notable, reinforcing the resurgence of a field...
BioCentury | May 16, 2017
Distillery Therapeutics

Cancer

...INDICATION: Breast cancer Cell culture and mouse studies suggest inhibiting GPNMB or its regulator MAFK could...
...with normal MAFK and GPNMB expression. In a mouse allograft model of advanced breast cancer, MAFK...
...testing inhibition of MAFK or GPNMB in animal models of other breast cancer subtypes. TARGET/MARKER/PATHWAY: MAF bZIP transcription factor K (MAFK)...
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