19:11 , Feb 21, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Melanoma Cell culture and mouse studies suggest activating or overexpressing NCR2 could help treat melanoma. In a human melanoma cell line, supernatant from NK cells activated by the NCR2 ligand PDGFDD decreased growth compared with...
22:56 , Jan 26, 2018 |  BC Extra  |  Financial News

Ping An hires COO, CMO

Ping An Insurance Co. of China Ltd. (HKSE:2318; Shanghai:601318) hired Donald Lacey as managing director and COO and Marco Huesch as managing director and CMO of the Ping An Global Voyager Fund. Lacey was managing...
22:16 , Aug 4, 2017 |  BioCentury  |  Finance

Milestone's options

Milestone Pharmaceuticals Inc. turned positive Phase II data for etripamil into an upsized $55 million series C round, which will give the cardiovascular company leeway to expand its core program or in-license a second cardio...
22:01 , Aug 1, 2017 |  BC Extra  |  Financial News

Milestone raises $55M in series C

Milestone Pharmaceuticals Inc. (Montreal, Quebec) raised $55 million in a series C round led by Novo Holdings A/S (Hellerup, Denmark). New investors Forbion Capital Partners and Tekla Capital Management also participated, as did existing investors...
17:27 , Feb 7, 2017 |  BC Extra  |  Financial News

Prexton raises EUR 29M in series B round

Neurology company Prexton Therapeutics S.A. (Plan-les-Ouates, Switzerland) raised EUR 29 million ($31.2 million) in a series B round co-led by Forbion Capital Partners and Seroba Life Sciences. Also participating were prior investors MS Ventures, Ysios...
17:42 , Nov 15, 2016 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Stroke Mouse studies suggest neural precursor cells could help treat ischemic stroke. In a middle cerebral artery occlusion mouse model of ischemic stroke, IV mouse neural precursor cells decreased ischemic lesion size and the number...
07:00 , Oct 27, 2016 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Pain In vitro and mouse studies identified a peptide-based MOR agonist that could help treat pain. Chemical synthesis and in vitro testing of analogs of a cyclic Phe-D-Pro-Phe-Trp peptide yielded a compound that selectively bound...
07:00 , Sep 15, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Macrophage receptor with collagenous structure (MARCO; SCARA2); lymphocyte antigen 6 complex locus G (Ly6g; Gr1)

Cancer INDICATION: Chronic lymphocytic leukemia (CLL) Studies in mice suggest depleting macrophages and neutrophils could help treat CLL. In an adoptive transfer mouse model of CLL, macrophage depletion decreased splenic tumor load compared with no depletion. In...
07:00 , Jul 28, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Spermidine/spermine N1-acetyltransferase 1 (SAT1; SSAT); ornithine decarboxylase (ODC)

Infectious disease INDICATION: Chikungunya virus; viral infection Studies in mammalian cell culture, fruit flies and zebrafish suggest promoting SAT1 expression or inhibiting ODC could help treat Chikungunya, Sindbis and Zika viral infections. In a hamster kidney...
07:00 , Jul 14, 2016 |  BC Extra  |  Politics & Policy

RACE for Children Act would require pediatric cancer studies

Legislation introduced in the U.S. House and Senate seeks to promote research on pediatric cancer therapies by modifying the Pediatric Research Equity Act (PREA). The newly introduced Research to Accelerate Cures and Equity for Children...