PlaqueTec Ltd. is working to bring personalized medicine to the cardiovascular space with a device that samples local concentrations of molecules near atherosclerotic plaques. By using these samples to identify prognostic and predictive biomarkers, the...
...identifying and testing ALOX12 inhibitors in models of ischemia/reperfusion-induced liver injury. TARGET/MARKER/PATHWAY: Arachidonate 12-lipoxygenase (ALOX12; 12-LOX... ...Hongliang Li, Renmin Hospital of Wuhan University, Wuhan, China email: firstname.lastname@example.org
Arachidonate 12-lipoxygenase (ALOX12) (12-LOX...
...Pharmaxis Ltd. has the LOXL2 inhibitor PXS-5033A in preclinical testing to treat liver fibrosis. TARGET/MARKER/PATHWAY: Lysyl oxidase-like... ...doi:10.1158/0008-5472.CAN-16-3152 CONTACT: Amparo Cano, Autonomous University of Madrid, Madrid, Spain email: email@example.com
Autonomous University of Madrid
...could help treat breast cancer. In in vitro LOX activity assays, a thiophenylmethanamine-based compound inhibited LOX... ...with vehicle. Next steps include clinical testing of the compound in breast cancer patients. TARGET/MARKER/PATHWAY: Lysyl oxidase (LOX)... ...Richard Marais, University of Manchester, Manchester, U.K. email: firstname.lastname@example.org
The Institute of Cancer Research
University of Manchester
Lysyl oxidase (LOX)...