BioCentury | Jun 4, 2019
Distillery Therapeutics

RELMα and RETN for Gram-positive and Gram-negative bacterial infections

...and Gram-negative Pseudomonas aeruginosa , mouse RELMα or human RETN decreased proliferation compared with chicken lysozyme...
BioCentury | Feb 7, 2019
Preclinical News

Novo, MIT develop oral biologic delivery device

...or other adverse effects. The team also showed that manufacturing SOMA devices loaded with insulin, lysozyme...
BioCentury | Jan 11, 2017
Distillery Techniques

Drug platforms

...the allosteric CCR9 antagonist Traficet-EN vercirnon and a 329-residue region of CCR2 fused to T4 lysozyme...
BioCentury | Apr 7, 2016
Translation in Brief

Knowing when to fold

...Liston. Because overexpression of multiple proteins, including biochemical markers such as GFP and hen egg lysozyme...
...the group crossed the NOD mice to a mouse line it had engineered to overexpress lysozyme (LYZ)...
...and GLIS3 is involved in β cell development. The team then showed that overexpression of LYZ...
BioCentury | Apr 7, 2016
Distillery Techniques

Disease models

...TECHNOLOGY: Transgenics and knockoutsGLIS3-knockout mice transgenically expressing chicken LYZ in pancreatic β cells could be useful...
...and Type II diabetes. In mice, systemic heterozygous knockout of GLIS3 and transgenic expression of LYZ... Fold," page 16). DESCRIPTION: GLIS family zinc finger 3 (GLIS3)-knockout mice transgenically expressing chicken lysozyme (LYZ)...
BioCentury | Apr 23, 2015
Distillery Techniques

Techniques: Antibody-based protease inhibitors

...inhibitors with high target affinity and specificity. The CDR3H loop of a human antibody against lysozyme...
BioCentury | Jul 12, 2012
Distillery Therapeutics

Indication: Infectious disease

...that confers pesticin resistance. Crystallography and bacterial growth assays were used to engineer a hybrid pesticin-lysozyme...
BioCentury | May 3, 2012
Tools & Techniques

Evolution not revolution

...acid aptamers that bound to the HIV transactivation response (TAR) element and to hen egg lysozyme...
BioCentury | Apr 8, 2010
Distillery Techniques

Technology: Drug delivery

...the cell-penetrating peptide LMWP linked to an antigen. In mice, topical application of LMWP-albumin and LMWP-lysozyme...
BioCentury | Sep 25, 2008
Distillery Techniques

This Week in Techniques regulate membrane protein overexpression by tuning T7 RNA polymerase levels with its inhibitor T7 lysozyme...
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