07:00 , Apr 11, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Bacteriophage T4 co-delivery of DNA and proteins for prime-boost vaccines Cell culture and mouse...
08:00 , Jan 31, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Sortase-mediated modification of a targeted mAb to improve antigen delivery and presentation Sortase-mediated modification of therapeutic mAbs could be...
07:00 , Apr 28, 2011 |  BC Innovations  |  Tools & Techniques

Next-generation dendritic cell vaccines

Vaccine makers have known for years that delivering immunogenic antigens to dendritic cells can elicit the strong T cell-based immune response that is key to combating viral and bacterial infections and cancer. But complexities of...
07:00 , Oct 7, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) Lymphocyte antigen 75 (LY75; DEC-205); proteolipid protein 1...
07:00 , Aug 19, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS Lymphocyte antigen 75 (LY75; DEC205); HIV p24 A study in mice identified DEC205-targeting mAbs...
07:00 , Mar 27, 2008 |  BC Innovations  |  Cover Story

Antigens by Special Delivery

DNA vaccines often require high and repeated dosing of antigen, which suggests suboptimal priming of the immune system and results in weak immunogenicity.1 Separate papers in Nature Biotechnology and the Journal of Clinical Investigationnow show...