BioCentury | Feb 12, 2015
Targets & Mechanisms

High five for Arsanis

...most potent cross-neutralizing toxin mAb had affinities for the monomeric toxins aHL, HLgB , and LukF...
...LukD - leukocidin D subunit LukE - leukocidin E subunit LukF ( LukF-PV ) - Panton-Valentine leukocidin chain F precursor...
...leukocidin F subunit LukF-G (LukG); leukocidin S subunit LukS-H (LukH); Panton-Valentine leukocidin chain F precursor ( LukF-PV ; LukF...
BioCentury | Sep 29, 2011
Distillery Therapeutics

Indication: Infectious disease

...Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Staphylococcus Panton-Valentine leukocidin (LukS-PV; pv); Panton-Valentine leukocidin chain F precursor (LukF-PV)...
...eye inflammation induced by the S. aureus toxin leukocidin, heavy chain-only antibodies targeting LukS-PV and/or LukF-PV...
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