04:35 , Aug 1, 2019 |  BC Innovations  |  Distillery Therapeutics

Sensitizing cancer to checkpoint inhibitors by targeting the non-coding RNA LINC01139

DISEASE CATEGORY: Cancer INDICATION: Breast cancer Blocking the long non-coding RNA LINC01139 could sensitize checkpoint inhibitor-resistant triple-negative breast cancer (TNBC) to the therapies. High LINC01139 expression levels correlated with low tumor levels of antigen-presenting cells...
19:10 , Feb 22, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Breast cancer Patient sample, cell culture and mouse studies suggest inhibiting LINC01139 could help treat breast cancer. In patient samples, low LINC01139 expression correlated with increased survival. In a human breast cancer cell line-based...