BioCentury | Nov 20, 2020
Deals

After three-target Lilly deal, Precision BioSciences hunting for more partnerships

...gene correction pipeline are programs for familial amyloid polyneuropathy, hemophilia A, autosomal dominant retinitis pigmentosa, lipoprotein lipase...
BioCentury | Jun 27, 2020
Deals

Who’ll buy uniQure now?

...market. The EC granted Glybera alipogene tiparvovec five-year conditional marketing approval in 2012 for lipoprotein lipase...
BioCentury | Sep 7, 2019
Product Development

Regeneron’s evinacumab data could make it the therapy of choice in HoFH

...lipids. The belief is that ANGPTL3 acts as an inhibitor of lipoprotein lipase and endothelial lipase...
BioCentury | Jun 27, 2019
Distillery Techniques

Patient-derived liver organoids for screening steatohepatitis

...accumulation in and death of organoids derived from patients with Wolman disease, a lysosomal acid lipase...
BioCentury | Jun 18, 2019
Company News

Latest twist in uniQure’s tale: possible sale

...decided not to pursue renewing Glybera’s European marketing authorization, citing limited uptake of the lipoprotein lipase...
...AMT-061, is in Phase III testing for hemophilia B. Jonathan Block, Associate Editor Pfizer Pfizer Inc. uniQure uniQure N.V. Vivet Therapeutics Lipoprotein lipase...
BioCentury | Jun 17, 2019
Company News

Trial data suggest 80% of Zynteglo patients could meet milestones in outcomes-based pricing model

...Chiesi Farmaceutici S.p.A. (Parma, Italy), which was approved in Europe in 2012 to treat lipoprotein lipase...
BioCentury | May 6, 2019
Company News

Lundbeck’s $250M Abide takeout lands Tourette compound, discovery hub

...2-AG - 2-arachidonoylglycerol; MGLL (MAGL) - Monoglyceride lipase Chris Lieu, Staff Writer ABX-1431 Abide Therapeutics Inc. H. Lundbeck A/S Monoglyceride lipase...
BioCentury | Oct 12, 2018
Clinical News

Phase II data for Merck's Btk inhibitor highlighted at ECTRIMS

...adverse events included reversible and asymptomatic increases in alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lipase...
BioCentury | Oct 12, 2018
Clinical News

Phase II data for Merck's Btk inhibitor highlighted at ECTRIMS

...adverse events included reversible and asymptomatic increases in alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lipase...
BioCentury | Aug 31, 2018
Clinical News

Priority Review for Alexion's long-acting PNH therapy

...pediatric disease vouchers in 2015 upon approval of Kanuma sebelipase alfa to treat lysosomal acid lipase...
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