BioCentury | Feb 1, 2019
Product R&D

BlueRock’s PD purity play

...a critical intermediate known as the floor plate midbrain progenitor cell, which expresses the markers LMX1A...
...Calif. Targets DAT1 (SLC6A3) - Solute carrier family 6 neurotransmitter transporter dopamine member 3 LMX1A (LMX1...
BioCentury | Aug 16, 2017
Distillery Therapeutics

Neurology

...PD. The reprogramming therapy involves lentiviral vectors encoding the dopaminergic neuron transcription factors ASCL1 , LMX1A...
...Achaete-scute family bHLH transcription factor 1 (ASCL1; MASH1); LIM homeobox transcription factor 1 α (LMX1A; LMX1...
...Kim, Dongguk University, Seoul, South Korea email: jk2316@gmail.com Hongjiang Li Achaete-scute complex homolog 1 (ASCL1) (MASH1) LIM homeobox transcription factor 1 alpha (LMX1A) (LMX1) Nuclear...
BioCentury | Sep 15, 2016
Distillery Techniques

Techniques: Mice with midbrain neuron-specific knockout of LIM homeobox transcription factor 1 α (LMX1A; LMX1) and LMX1B as a model of Parkinson's disease (PD)

...Disease models TECHNOLOGY: Transgenics and knockouts LMX1A /LMX1B-knockout mice could be useful for screening therapies to...
.../LMX1B-knockout mice could be useful for screening therapies to treat PD. In mice, knockout of LMX1A...
...therapies. DESCRIPTION: Mice with midbrain neuron-specific knockout of LIM homeobox transcription factor 1 α (LMX1A; LMX1...
BioCentury | Jul 16, 2012
Company News

Echo Therapeutics, Ferndale Pharma Group deal

The partners added Argentina, Brazil, Chile, Belgium, France, Germany, Italy, the Netherlands, Spain, Sweden, Switzerland, Austria, Australia and New Zealand to a 2009 deal granting Ferndale exclusive rights to develop and commercialize Prelude SkinPrep System...
BioCentury | Jul 28, 2011
Distillery Techniques

Technology: Drug platforms

...subfamily 4 group A member 2 (NR4A2; NURR1) and LIM homeobox transcription factor 1 (LMX1A; LMX1)-were...
BioCentury | Jun 8, 2009
Company News

Echo Therapeutics, Ferndale Pharma Group deal

Echo granted Ferndale an exclusive license to develop and commercialize Prelude SkinPrep System in North America and the U.K. for transdermal analgesic and anesthetic drug delivery applications. Echo will submit a 510(k) in 3Q09. Ferndale...
BioCentury | May 7, 2009
Distillery Techniques

Technology: Drug platforms

...factor 1a (LMX1A) expression for efficient production of mesencephalic dopamine (mesDA) neurons Forced expression of LMX1A...
...mesDA neurons for use in cell replacement therapies. In mouse ES cells, forced expression of Lmx1a...
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