18:00 , Aug 16, 2017 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Parkinson’s disease (PD); neurology Mouse studies suggest electromagnetized nanoparticle-mediated...
07:00 , Sep 15, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Mice with midbrain neuron-specific knockout of LIM homeobox transcription factor 1 α (LMX1A; LMX1) and LMX1B as a model of Parkinson's disease (PD)

Disease models TECHNOLOGY: Transgenics and knockouts LMX1A /LMX1B-knockout mice could be useful for screening therapies to treat PD. In mice, knockout of LMX1A and LMX1B in midbrain dopaminergic neurons recapitulated the oxidative stress in midbrain...
07:00 , Jul 28, 2011 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Generation of induced dopaminergic (iDA) cells from skin fibroblasts A method for generating iDA cells from skin fibroblasts could provide a cell-based therapy for Parkinson's...
07:00 , May 7, 2009 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms LIM homeobox transcription factor 1a (LMX1A) expression for efficient production of mesencephalic dopamine (mesDA) neurons Forced expression of LMX1A could be...