BC Innovations | Nov 30, 2018
Targets & Mechanisms

Revving up metabolism at ASH 2018

Cancer metabolism is a prominent theme at this year’s ASH meeting, with researchers broadening the tent from metabolic targets that drive hematologic malignancies to those that intersect with other hot topics, notably immuno-oncology and epigenetics....
BC Innovations | Mar 31, 2016
Translation in Brief

Neighborhood loops

Specialized loop regions in chromosomes hold the keys to why and how some proto-oncogenes get activated to cause cancer, according to a group at the Whitehead Institute for Biomedical Research . The findings could provide new...
BC Week In Review | Mar 4, 2013
Company News

Diagnovus sales and marketing update

Diagnovus launched the Engauge-cancer-DLBCL gene expression assay diagnostic tool worldwide to aid in the stratification and treatment of patients with diffuse large B cell lymphoma (DLBCL). The RT-PCR assay, conducted on paraffin-embedded primary DLBCL tissue,...
BioCentury | May 1, 2006
Tools & Techniques

Detective work

Although the heat from clinical and product blowups eventually subsides, researchers continue to try to elucidate the causes of the setbacks. Two recent academic reports shed such light, one expanding on the risks of COX-2...
BC Week In Review | Oct 20, 2003
Clinical News

Gamma-c gene therapy hematology data

Researchers published in Science previously reported results from a French study in 10 patients that showed uncontrolled exponential clonal proliferation of mature T cells occurred in 2 patients. Both patients' clones showed retrovirus vector integration...
BioCentury | Oct 7, 2002
Tools & Techniques

Gene therapy SCIDs

Last week's news that a patient in a French trial of gene therapy for the X-linked form of severe combined immune deficiency disease (XSCID) developed T cell lymphoproliferative disease renews concerns about the safety of...
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