BioCentury | Jun 9, 2008
Product Development

No regrets

...is chemically attached to monomethyl auristatin E (MMAE) via an enzyme-activated linker. SGN-15 was a Lewis Y antigen-targeted...
BioCentury | Nov 12, 2007
Company News

Crucell, DSM Biologics N.V., Recepta Biopharma S.A. deal

...to treat cancer: hu3S193; 58-1066; MX35; and A34(209-342). hu3S193 is a humanized MAb against the Lewis Y antigen...
BioCentury | Jul 17, 2006
Strategy

Wyeth's biologics pipeline

...conjugated to anti-CD22 MAb Non-Hodgkin's lymphoma (NHL) Ph I CMD-193 Calicheamycin conjugated to MAb against Lewis Y antigen...
BioCentury | Feb 13, 2006
Company News

Aphton, Celltrion deal

...license to commercialize Igeneon's next-generation antibody, IGN312, in the same territories. Both antibodies target the Lewis Y antigen...
BioCentury | Aug 1, 2005
Company News

Aphton, Celltrion deal

...commercialization rights to IGN311 in certain Asian countries, including Japan. The monoclonal antibody targeting the Lewis Y antigen...
BioCentury | Jul 25, 2005
Clinical News

IGN311: Phase I/II started

...up to 24 patients. Aphton Corp. (APHT), Miami, Fla. Product: IGN311 Business: Cancer Molecular target: Lewis Y antigen...
BioCentury | Jul 18, 2005
Clinical News

IGN311: Phase I data

...APHT), Miami, Fla. Product: IGN311 Business: Cancer Molecular target: Lewis Y antigen Description: Human monoclonal antibody against Lewis Y antigen...
BioCentury | Jul 11, 2005
Product Development

Generation next

...second-generation preclinical candidates. SGN-15, the lead first-generation ADC, is composed of a MAb targeting the Lewis Y antigen...
BioCentury | Jul 11, 2005
Clinical News

SGN-15: Development discontinued

...markets Taxotere docetaxel. Seattle Genetics Inc. (SGEN), Bothell, Wash. Product: SGN-15 Business: Cancer Molecular target: Lewis Y antigen...
BioCentury | May 16, 2005
Company News

Aphton cancer news

...Phase II/III trial to treat non-small cell lung cancer (NSCLC); IGN311, a MAb targeting the Lewis Y antigen...
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