01:01 , Jul 24, 2019 |  BC Extra  |  Company News

New flexibility and a new Celgene deal for Jounce

With BMS's acquisition of Celgene nearly complete, the big biotech and Jounce ended an immuno-oncology option deal on Tuesday, giving Jounce control over programs that would have overlapped with BMS's pipeline. But the companies will...
02:21 , Mar 29, 2019 |  BC Innovations  |  Targets & Mechanisms

AACR moves in a myeloid direction

Myeloid cells are showing up everywhere at this year’s AACR conference, suggesting the research community is rapidly expanding the ways it can harness the cell types to improve cancer immunotherapy responses. One of those ways...
00:15 , Mar 2, 2018 |  BC Innovations  |  Product R&D

Sigma for synapses

By focusing on synapse protection instead of aggregate formation, Cognition Therapeutics Inc. has identified a new target for Alzheimer’s disease that it believes can block β amyloid’s toxic effects more efficiently than the standard approaches....
07:00 , Oct 24, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2; LIR2) Cell culture and mouse studies suggest blocking LILRB2 could...
07:00 , Jun 14, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Leukemia Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2; LIR2) Mouse and cell culture studies suggest inhibiting the interaction between angiopoietin-like proteins and LILRB2 could...
08:00 , Dec 4, 2008 |  BC Innovations  |  Cover Story

New strategies for CNS regeneration

Two separate teams of company and university researchers have identified multiple neuronal proteins that could be targeted alone or in combination to promote axon growth and treat spinal cord injury and other forms of CNS...