BioCentury | Jun 29, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

...Techniques Neurology Autism Leucine rich repeat and fibronectin type III domain containing 2 (LRFN2) Genetic studies identified an association between autism and a SNP on LRFN2...
BioCentury | Jun 27, 2017
Distillery Techniques

Disease models

...TECHNOLOGY: Transgenics and knockouts LRFN2 -knockout mice could be use to screen autism therapies. Genetic association...
...and a SNP on LRFN2 (rs558275173). Mice with homozygous knockout of exon 2 of the LRFN2...
...subset of autism patients. Next steps could include using the model to screen therapies. DESCRIPTION: Leucine rich repeat and fibronectin type III domain containing 2 (LRFN2)-knockout...
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