BioCentury | Apr 22, 2019
Distillery Therapeutics

Inhibiting the LLGL2-SLC7A5-YKT6 complex for breast cancer

...CATEGORY: Cancer INDICATION: Breast cancer Patient sample, cell culture and mouse studies suggest inhibiting the LLGL2-SLC7A5-YKT6...
...growth compared with normal LLGL2 and SLC7A5 expression or vehicle. Next steps could include testing LLGL2...
...a synthetic amino acid that targets SLC7A5, in preclinical testing for glioblastoma. TARGET/MARKER/PATHWAY: Lethal giant larvae homolog 2 (LLGL2; LGL2...
BioCentury | Dec 10, 2009
Distillery Techniques

Technology: Disease models

...for screening cancer therapies. Wild-type zebrafish transplanted with lgl2-deficient epidermal cells developed epidermal tumors. The lgl2-deficent...
Items per page:
1 - 2 of 2