BioCentury | Dec 3, 2015
Distillery Therapeutics

Therapeutics: Latent transforming growth factor β binding protein 3 (LTBP3)

Cardiovascular disease INDICATION: Cardiovascular Mouse studies suggest inhibiting LTBP3 could help treat the cardiovascular pathology of Marfan syndrome, which is associated with high levels of transforming growth factor β (TGFβ) signaling. In a genetic mouse...
BioCentury | Nov 20, 2014
Distillery Therapeutics

Indication: Musculoskeletal disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Muscular dystrophy Latent transforming growth factor-b binding protein 4 (LTBP4) Mouse studies suggest inhibiting cleavage of LTBP4 could help treat muscular dystrophies. In mouse...
BioCentury | May 28, 2009
Distillery Therapeutics

Indication: Ophthalmic disease

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Ophthalmic disease Blindness; glaucoma Latent transforming growth factor-b binding protein 2 (LTBP2) A genetic study in humans and in mice suggests...
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