BC Innovations | Oct 9, 2014
Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) UDP-Gal:bGlcNAc b-1,4- galactosyltransferase polypeptide 6 (B4GALT6); lactosylceramide Studies in patient samples and mice suggest inhibiting B4GALT6 could help treat MS. In...
BC Innovations | Jul 1, 2010
Targets & Mechanisms

PKD: cease and de-cyst

Marketed treatments for polycystic kidney disease manage symptoms but do not slow disease progression. A research team led by Genzyme Corp. now has shown that blocking biosynthesis of the glycosphingolipid glucosylceramide could help treat the...
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