BC Innovations | Apr 16, 2015
Distillery Therapeutics

Therapeutics: KISS1 receptor (KISS1R; GPR54); KISS-1 metastasis suppressor (KISS1; kisspeptin)

Endocrine/metabolic disease INDICATION: Hypogonadism In vitro and sheep studies suggest a kisspeptin-based lipopeptide could help treat hypogonadotropic hypogonadism caused by low levels of luteinizing hormone. The lipopeptide consisted of an endogenous kisspeptin peptide modified with...
BC Innovations | Oct 17, 2013
Targets & Mechanisms

HER2's outside help

An international team has found that neurokinin 1 substance P receptor , a known player in nausea, pain and inflammation, enhances HER2 signaling in breast cancer. 1 The findings argue for combining antagonists against both receptors...
BC Innovations | Sep 15, 2011
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer KISS1 receptor (KISS1R; GPR54) In vitro and mouse studies suggest inhibiting KISS1R could help treat breast cancer. In a mouse model of breast...
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