BioCentury | Jun 10, 2010
Distillery Therapeutics

Indication: Neurology

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Depression; mania Kinesin light chain 2 (KLC2); glycogen synthase kinase...
...that inhibiting GSK3B-KLC2 signaling could help treat depression and mania. In cultured murine hippocampal neurons, Klc2...
...underlie long-term depression. In mouse hippocampal slices, a KLC2-derived mimic peptide led to blockade of Gsk3b-Klc2...
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