22:36 , Apr 4, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: March 2018

New Therapeutic Targets and Biomarkers: March 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during March 2018. Therapeutic targets are defined as any protein, gene or other molecule...
18:13 , Apr 3, 2018 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: SNPs Loss-of-function variants and a SNP on KIF5A could help predict the risk of ALS. Genome-wide association studies (GWAS) in 24,965 ALS patients and 78,364 healthy volunteers identified associations between a SNP on KIF5A (rs113247976)...
17:56 , Mar 23, 2018 |  BC Extra  |  Preclinical News

KIF5A mutations a cause of ALS

In a paper published in Neuron, an international consortium of researchers identified loss-of-function mutations in the kinesin family member 5A (KIF5A) gene as a cause of amyotrophic lateral sclerosis through large-scale genome studies combined with...