15:41 , Jul 18, 2018 |  BC Innovations  |  Distillery Techniques

Assays and screens

TECHNOLOGY: Cellular assays A chicken embryo-based method of screening genes required for tumor cell motility could identify new targets for cancer metastasis. The method involves six steps: transducing metastatic cancer cells with a human shRNA...
01:00 , Feb 17, 2017 |  BC Innovations  |  Targets & Mechanisms

Gilding the Goldfinch

In launching Goldfinch Biopharma Inc. , Third Rock is extending its already heavy footprint in precision medicine into chronic kidney disease. The VC thinks the unfolding genetics in that field can yield disease-modifying therapies and...
07:00 , Sep 17, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Basal cell carcinoma (BCC) Kinesin family member 3A (KIF3A); intraflagellar transport 88 homolog (IFT88) A study in mice and human tissue suggests that antagonizing...
07:00 , Sep 17, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Cancer Medulloblastoma Kinesin family member 3A (KIF3A) A study in human tissue and mice suggests that antagonizing KIF3A could help treat medulloblastoma. KIF3A is involved...
07:00 , Sep 17, 2009 |  BC Innovations  |  Targets & Mechanisms

The Hedgehog's spine

The primary cilium, a lone spiky protrusion on the cell surface, once was thought to be a functionless vestige of humankind's unicellular past. However, genetic defects in the primary cilium turned out to be linked...