08:00 , Nov 6, 2014 |  BC Innovations  |  Distillery Techniques

Technology: Computational models

Approach Summary Licensing status Publication and contact information Computational models Driver-gene inference by genetic-genomics and information theory (DIGGIT) algorithm to identify disease driver mutations In vitro studies suggest network-based analysis with DIGGIT could help identify...
07:00 , Sep 6, 2012 |  BC Innovations  |  Targets & Mechanisms

Passenger mutations take the wheel

Two research groups have independently shown that targeting genes carrying passenger mutations blocked growth of cancer cells and improved survival in mouse models. 1,2 Although precise therapeutic windows for such a strategy remain to be...