BioCentury | Oct 25, 2018
Distillery Therapeutics

Neurology

...INDICATION: Pain Rat studies suggest promoting the expression of TRESK or inhibiting its negative regulators VEGF...
...help treat pain associated with bone metastasis. In a rat model of bone metastasis-associated pain, TRESK...
...testing promoters of TRESK expression in models of metastasis-associated pain. TARGET/MARKER/PATHWAY: Potassium channel K2p18.1 (KCNK18; TRESK...
BioCentury | Dec 19, 2013
Translation in Brief

Translational tidbits

...University of Oxford Neurology Undisclosed Partnership to screen selective and potent potassium channel K2p18.1 (KCNK18; TRESK...
BioCentury | Nov 18, 2013
Company News

MRC, University of Oxford deal

...KCNK18 ; TRESK ) activators to develop compounds to treat migraines. According to the partners, KCNK18...
BioCentury | Oct 7, 2010
Distillery Therapeutics

Indication: Neurology

...Neurology Migraine Potassium channel K2p18.1 (KCNK18; TRESK) In vitro and patient sample studies suggest that TRESK...
...agonists could help prevent or treat migraine with aura. In patient samples, genetic sequencing of TRESK...
...migraine patients with mutations in TRESK and developing a mouse model that expresses the mutated TRESK...
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