...INDICATION: Pain Rat studies suggest promoting the expression of TRESK or inhibiting its negative regulators VEGF...
...help treat pain associated with bone metastasis. In a rat model of bone metastasis-associated pain, TRESK...
...testing promoters of TRESK expression in models of metastasis-associated pain. TARGET/MARKER/PATHWAY: Potassium channel K2p18.1 (KCNK18; TRESK...

...University of Oxford Neurology Undisclosed Partnership to screen selective and potent potassium channel K2p18.1 (KCNK18; TRESK...

...KCNK18 ; TRESK ) activators to develop compounds to treat migraines. According to the partners, KCNK18...

...Neurology Migraine Potassium channel K2p18.1 (KCNK18; TRESK) In vitro and patient sample studies suggest that TRESK...
...agonists could help prevent or treat migraine with aura. In patient samples, genetic sequencing of TRESK...
...migraine patients with mutations in TRESK and developing a mouse model that expresses the mutated TRESK...