BioCentury | Aug 4, 2016
Product R&D

Antibiotic wisdom

...HK3, TNIP1, GPAA1, and cathepsin B - during bacterial infection and three - IFI27, JUP...
...attachment 1 HK3 - Hexokinase 3 IFI27 - Interferon α inducible protein 27 JUP - Junction plakoglobin...
BioCentury | Sep 18, 2014
Distillery Therapeutics

Indication: Cancer

...Publication and contact information Cancer Breast cancer Junction plakoglobin (JUP) Studies in mice and patient samples suggest JUP...
...greater JUP expression than matched single CTCs. In mice injected with human breast CTC clusters, JUP-targeting...
...decreased lung metastasis compared with control shRNA. Next steps include developing strategies that can lower JUP...
BioCentury | Jul 24, 2014
Distillery Techniques

Technology: Disease models

...arrhythmogenic cardiomyopathy could help drug discovery in the indication. In transgenic zebrafish, a mutation in junction plakoglobin (Jup)...
...three months compared with no treatment. In cultured neonatal rat ventricular myocytes expressing the mutant Jup...
BioCentury | Feb 28, 2013
Tools & Techniques

Cardiomyocytes acting like adults

...identified in subunits of desmosomes on cardiac cells that help glue the cells together, including junction plakoglobin (JUP)...
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