BioCentury | Jun 6, 2013
Distillery Therapeutics

Indication: Other

...status Publication and contact information Other Progeria Isoprenylcysteine carboxyl methyltransferase (ICMT) Mouse and cell culture studies suggest inhibiting ICMT...
...wild-type Icmt. In fibroblasts from patients with HGPS, ICMT-targeting small hairpin RNA or a competitive ICMT...
...increased proliferation compared with control shRNA or vehicle. Next steps include testing Icmt knockdown or ICMT...
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