BioCentury | May 4, 2018
Company News

Accelerator launches Proniras to develop anticonvulsant

Accelerator Life Science Partners (Seattle, Wash.) launched newco Proniras Corp. (Seattle, Wash.) to develop tezampanel (LY293558) to treat nerve agent-induced seizures. Proniras has received an $89.5 million award from HHS’s Biomedical Advanced Research and Development...
BioCentury | May 3, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: April 2018

New Therapeutic Targets and Biomarkers: April 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during April 2018. Therapeutic targets are defined as any protein, gene or other...
BioCentury | Apr 27, 2018
Company News

Accelerator launches Proniras to develop anticonvulsant

Accelerator Life Science Partners (Seattle, Wash.) launched newco Proniras Corp. (Seattle, Wash.) to develop tezampanel (LY293558) to treat nerve agent-induced seizures. Proniras has received an $89.5 million award from HHS’s Biomedical Advanced Research and Development...
BioCentury | Nov 12, 2015
Distillery Techniques

Techniques: Transgenic ionotropic glutamate receptor kainate 4 (GRIK4)-expressing mouse model of autism spectrum disorder (ASD)

...Disease modelsTransgenic mice expressing rat GRIK4 could be used to screen for therapies to treat ASD...
...could be used to screen for therapies to treat ASD. Mice engineered to express rat GRIK4...
...vehicle. Next steps could include using the model to test therapeutic candidates to treat ASD. ionotropic glutamate receptor kainate 4 BC...
BioCentury | Oct 9, 2008
Distillery Therapeutics

This Week in Therapeutics

...receptor, ionotropic, kainate 4 (GRIK4; KA1) A genotyping study suggests that a deletion mutation in GRIK4...
...an independent replication cohort with 274 patients and 376 healthy controls. Kainate receptor expression and GRIK4...
...been implicated in the pathophysiology of schizophrenia. Next steps include studying how the mutation affects GRIK4...
BioCentury | Oct 8, 2007
Clinical News

Celexa citalopram neurology data

Researchers from NIH's National Institute of Mental Health (NIMH), the University of Texas Southwestern Medical School and colleagues reported in the American Journal of Psychiatry that 2 SNPs within the GRIK2 and GRIA3 genes were...
BioCentury | Oct 3, 2007
Clinical News

Genetic markers of suicidal ideation proposed

Researchers from NIH's National Institute of Mental Health (NIMH), the University of Texas Southwestern Medical School and colleagues reported in the American Journal of Psychiatry that two SNPs within the GRIK2 and GRIA3 genes were...
Items per page:
1 - 7 of 7