07:00 , Apr 16, 2015 |  BC Innovations  |  Product R&D

Antagonizing psoriasis

Despite the heavy competition in psoriasis, AnaptysBio Inc. believes it can make a mark with a first-in-class antibody for a neglected, inherited form of pustular psoriasis caused by a loss-of-function mutation in the proinflammatory cytokine...
07:00 , Nov 1, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Autoimmune disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Psoriasis IL-1 receptor-like 2 (IL1RL2; IL-36R) Mouse studies suggest antagonizing IL-36R could help treat psoriasis. In a mouse model of psoriasis, knocking out Il-36r...