17:55 , Aug 29, 2018 |  BC Innovations  |  Distillery Therapeutics

Inflammation

INDICATION: Inflammation Cell culture, mouse, rat and dog studies identified a RORγT inverse agonist that could help treat inflammation. Chemical synthesis and screening of a subset of Pfizer Inc.’s small compound library in a HEK-cell based...
17:33 , Jul 20, 2018 |  BC Week In Review  |  WIR Deals New Deals

Novartis in atopic dermatitis deal with MorphoSys, Galapagos

MorphoSys AG (Xetra:MOR; NASDAQ:MOR) and Galapagos N.V. (Euronext:GLPG; NASDAQ:GLPG) granted Novartis AG (NYSE:NVS; SIX:NOVN) exclusive, worldwide rights to MOR106, a mAb against IL-17C that is in Phase II testing for atopic dermatitis. MorphoSys and Galapagos will...
20:37 , Jul 19, 2018 |  BC Extra  |  Company News

Novartis in atopic dermatitis deal with MorphoSys, Galapagos

MorphoSys AG (Xetra:MOR; NASDAQ:MOR) and Galapagos N.V. (Euronext:GLPG; NASDAQ:GLPG) granted Novartis AG (NYSE:NVS; SIX:NOVN) exclusive, worldwide rights to MOR106, a mAb against IL-17C that is in Phase II testing for atopic dermatitis. MorphoSys and Galapagos will...
18:21 , Jun 29, 2018 |  BC Week In Review  |  Clinical News

Lilly's Taltz meets in Phase III for TNF inhibitor-experienced ankylosing spondylitis

Eli Lilly and Co. (NYSE:LLY) said Taltz ixekizumab met the primary endpoint of a greater proportion of patients achieving an Assessment of Spondyloarthritis International Society 40 (ASAS40) response at week 16 vs. placebo in the...
19:42 , May 18, 2018 |  BC Week In Review  |  Clinical News

Novartis to start head-to-head trial of Cosentyx and Tremfya

Novartis AG (NYSE:NVS; SIX:NOVN) plans to begin the head-to-head Phase IIa ARROW trial to compare Cosentyx secukinumab to Tremfya guselkumab for 16 weeks in 40 patients with Stelara ustekinumab-resistant plaque psoriasis. The pharma expects to...
17:43 , May 11, 2018 |  BC Week In Review  |  Clinical News

Lilly’s Taltz meets in Phase III for ankylosing spondylitis

In February, Eli Lilly and Co. (NYSE:LLY) reported top-line data from the Phase III COAST-V trial to treat axial spondyloarthritis showing that subcutaneous Taltz ixekizumab met the primary endpoint of a greater proportion of patients...
22:15 , Apr 24, 2018 |  BC Extra  |  Company News

Diabetes franchise drives 1Q18 for Lilly

Strong sales from the diabetes franchise of Eli Lilly and Co. (NYSE:LLY) led to 1Q18 results that outpaced consensus estimates. On Tuesday, the pharma reported revenue of $5.7 billion for the period, up 9% from...
21:45 , Apr 19, 2018 |  BC Extra  |  Company News

Novartis reports first Kymriah sales, Cosentyx miss

Novartis AG (NYSE:NVS; SIX:NOVN) reported $580 million in 1Q18 sales of autoimmune drug Cosentyx secukinumab, shy of analysts' $635 million consensus estimate. The pharma also reported for the first time sales of CAR T therapy...
20:58 , Apr 6, 2018 |  BC Week In Review  |  Clinical News

Oxford BioDynamics reports data for predicting inadequate responders to methotrexate

Oxford BioDynamics plc (LSE:OBD) and colleagues reported that the presence of a five-marker Chromosome Confirmation Signature (CCS) in the blood of patients with early rheumatoid arthritis as detected by the company's EpiSwitch epigenetic biomarker platform...
02:44 , Mar 10, 2018 |  BioCentury  |  Product Development

Virtual leap

Novartis AG’s decision to expand a collaboration with mobile technology and clinical trials management company Science 37 Inc. fits squarely within CEO Vasant Narasimhan’s oft-stated plans to use digital health to speed drug development. The...