BioCentury | Nov 11, 2020
Emerging Company Profile

CatalYm: opening up tumors to immune cells

...of use TARGETSGDF15 – Growth differentiation factor 15GFRAL – GDNF family receptor alpha likeICAM-1 (CD54) – Intercellular adhesion molecule-1LFA-1...
BioCentury | Aug 29, 2019
Distillery Therapeutics

Tumor-targeted nanoparticle delivery of gene editing therapy for breast cancer

...therapeutic gene editing in other cancer types (see "Nanoparticles Targeting CRISPR to Cancer" ). TARGET/MARKER/PATHWAY: Intercellular adhesion molecule-1...
...CONTACT: Debra T. Auguste, Northeastern University, Boston, Mass. e-mail: d.auguste@northeastern.edu Sandi Wong Boston Children's Hospital Harvard Medical School Northeastern University Intercellular adhesion molecule-1...
BioCentury | Aug 28, 2019
Translation in Brief

Nanoparticles targeting CRISPR to cancer

...NGAL) - Lipocalin 2; ICAM-1 (CD54) - Intercellular adhesion molecule-1 Sandi Wong, Staff Writer Boston Children's Hospital Harvard Medical School Northeastern University Intercellular adhesion molecule-1...
BioCentury | Apr 2, 2019
Distillery Techniques

Dual-targeting liposomes for cancer therapy delivery

...Screening of three human triple-negative breast cancer (TNBC) cell lines against the 68-gene panel identified intercellular adhesion molecule-1...
...Children’s Hospital, Boston, Mass. enmail: marsha.moses@childrens.harvard.edu Claire Quang Boston Children's Hospital Northeastern University Epidermal growth factor receptor (EGFR) (ErbB1) (HER1) Intercellular adhesion molecule-1...
BioCentury | Sep 5, 2018
Preclinical News

Two papers open door to T cell brain entry for glioblastoma therapy

...cells can complete migration after detecting a second wave of cell adhesion molecules, led by intercellular adhesion molecule-1...
BioCentury | Jul 19, 2018
Translation in Brief

Inflammatory images

...recruits additional monocytes and macrophages from outside the kidney in a process that depends on intercellular adhesion molecule-1...
...published work. University of Calgary has not patented the work. Sandi Wong, Staff Writer University of Calgary Dehydropeptidase I Intercellular adhesion molecule-1...
BioCentury | May 25, 2018
Clinical News

Bavarian Nordic's ProstVac misses OS endpoint in Phase III for CRPC

...prostate-specific antigen (PSA; KLK3) that contains a Tricom triad of costimulatory molecules -- CD58 (LFA-3), intercellular adhesion molecule-1...
...Description: Vaccine targeting PSA that contains a Tricom triad of costimulatory molecules -- CD58 (LFA-3), intercellular adhesion molecule-1...
BioCentury | Feb 23, 2018
Company News

Merck buying oncolytic virus play Viralytics for $398M

...Australia Merck & Co. Inc. (NYSE:MRK), Kenilworth, N.J. Business: Cancer Jaime De Leon Cavatak CVA21 Merck & Co. Inc. Viralytics Ltd. Intercellular adhesion molecule-1...
BioCentury | Feb 21, 2018
Company News

Merck buying oncolytic virus play Viralytics for $398M

...Wednesday. Jaime De Leon BMS-734016 Cavatak CVA21 ipilimumab Keytruda MDX-010 MDX-CTLA-4 MK-3475 pembrolizumab Yervoy Bristol-Myers Squibb Co. Merck & Co. Inc. Viralytics Ltd. Cytotoxic T-lymphocyte associated protein 4 (CTLA-4) (CTLA4) (CD152) Intercellular adhesion molecule-1...
BioCentury | Jan 31, 2018
Distillery Techniques

Drug delivery

...receptors -- including CUB domain containing protein 1 (CDCP1; CD318), ecto-5’-nucleotidase (NT5E; NT; CD73) and intercellular adhesion molecule-1...
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