BioCentury | Aug 1, 2016
Product Development

IGF synergy in cancer

...oncology clinical program leader. He said IGF-2 not only signals through IGF1R, but also through insulin receptor isoform A (IR-A)...
BioCentury | Apr 11, 2011
Product Development

Ligand approach to IGF

...tumors can develop resistance to mAbs against IGF1R by increasing expression of IGF-1, IGF-2 and insulin receptor isoform A (IR-A)...
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