07:00 , Apr 9, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Inositol polyphosphate-5-phosphatase D (INPP5D); spleen tyrosine kinase (SYK)

Cancer INDICATION: Acute lymphoblastic leukemia (ALL) In vitro and mouse studies suggest hyperactivating SYK could help treat tyrosine kinase inhibitor (TKI)-resistant ALL. Philadelphia chromosome-positive (Ph+) ALL cells from patients expressed higher levels of receptors that...
08:00 , Feb 5, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

This week in therapeutics Indication Target/ marker/ pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Inositol polyphosphate-5-phosphatase (INPP5D; SHIP) Studies in mice suggest that activating SHIP could be useful for preventing...