BC Innovations | Apr 24, 2018
Distillery Therapeutics

Infectious disease

INDICATION: Pneumonia Mouse studies suggest inhibiting IP6K1 could help treat bacterial pneumonia. In mouse models of E. coli- or Staphylococcus aureus- induced pneumonia, systemic IP6K1 knockout decreased bacterial burden, edema and neutrophil infiltration in the...
BC Innovations | Jan 6, 2011
Cover Story

Inositol insulin insight

A lack of druggable targets in the insulin-Akt pathway has made increasing insulin signaling an uphill struggle for metabolic disease companies. Indeed, there are no approved drugs that directly modulate Akt or other intracellular components...
BC Innovations | Jan 6, 2011
Distillery Therapeutics

Indication: Various

Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Obesity; metabolic syndrome Inositol hexakisphosphate kinase-1 (IP6K1) A study in cell culture and in mice suggests that antagonizing IP6K1 could help treat obesity and metabolic...
Items per page:
1 - 3 of 3