21:11 , Apr 17, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Influenza virus Mouse studies suggest mAbs against influenza A virus neuraminidase subtypes N1 or N2 could help prevent or treat influenza. In mouse challenge models of lethal H3N2 and H1N1 influenza infection, pre-challenge treatment with...
07:00 , Mar 21, 2013 |  BC Innovations  |  Targets & Mechanisms

Trapping influenza neuraminidase

Researchers at The University of British Columbia have used a mechanism-based approach to design irreversible inhibitors of influenza virus neuraminidase that could have activity against flu strains resistant to marketed inhibitors of the target.1 The...
08:00 , Dec 20, 2012 |  BC Innovations  |  Cover Story

Translating mRNA vaccines

A collaboration between CureVac GmbH and the Friedrich Loeffler Institute has produced in vivo evidence that an mRNA-based vaccine can prevent influenza A infection.1 The results provide proof of concept for the company's vaccine platform...
08:00 , Dec 20, 2012 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms mRNA vaccines to prevent influenza A infection Vaccination with a mixture of protamine-complexed mRNAs...
08:00 , Dec 20, 2012 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms mRNA vaccines to prevent influenza A infection Vaccination with a mixture of protamine-complexed mRNAs...
07:00 , Oct 20, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Influenza virus Influenza A virus neuraminidase (NA) In vitro studies identified...
08:00 , Jan 14, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Influenza virus Influenza A virus neuraminidase An in vitro study identified diarylheptanoid neuraminidase inhibitors that could...
07:00 , Jun 25, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Influenza virus Influenza...
07:00 , May 7, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease ...