20:24 , Oct 31, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer; infectious disease

INDICATION: Cancer; melanoma; cervical cancer; influenza virus Mouse and monkey studies suggest simvastatin could be used as an adjuvant to boost the efficacy of cancer and influenza vaccines. In mice, immunization with the antigen ovalbumin...
23:28 , Oct 3, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Influenza virus Mouse studies suggest a vaccine based on multiple conformations of an HA1 epitope could help prevent influenza A infection. Crystallographic analyses of HA1 from four strains of influenza A virus identified five...
17:07 , Feb 6, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Influenza virus Mouse studies suggest a protein nanoparticle vaccine based on M2e, HA1 and HA2 could help prevent influenza A virus infection. The vaccine consists of a mixture of nanoparticles, all having the same...
00:30 , Oct 12, 2017 |  BC Innovations  |  Product R&D

Artificial mini proteins

Virvio Inc. has spun out of a group from the University of Washington to develop artificial mini proteins as novel influenza therapeutics. The mini proteins, typically ranging between 30 and 50 amino acids in length,...
16:20 , Jun 20, 2017 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Influenza virus In vitro , cell culture and mouse studies suggest the frog skin peptide urumin could help treat HA1 -expressing influenza viral infection. In in vitro electron microscopy experiments, urumin decreased virion integrity...
07:00 , Aug 23, 2012 |  BC Innovations  |  Targets & Mechanisms

Broader is better

A team from the Crucell Vaccine Institute and The Scripps Research Institute has identified a trio of neutralizing human mAbs that protect mice from challenge with influenza viruses, including one mAb that protects against both...