...targeting T and B cells through inhibiting ICOSLG...
...TNF superfamily member 13bICOSLG (B7-H2; B7RP1) – Inducible T cell co-stimulator ligand Lauren...

...Zurich (ETHZ) Philogen S.p.A. Novartis AG Indiana University Medical University of South Carolina Alpine Immune Sciences Inc. Nordic Nanovector ASA Molecular Partners AG Inducible T cell co-stimulator ligand (ICOSLG) (B7-H2) (B7RP1) CD28 Inducible...

...Cytotoxic T-lymphocyte associated protein 4 ICOS - Inducible T cell co-stimulator ICOSL (B7-H2; B7RP1) - Inducible T cell co-stimulator ligand...

...INDICATION: Organ transplant rejection Mouse studies suggest inhibiting CXCL13, CD40L and ICOSLG, which play roles in...
...with a control IgG. Also in the model, an anti-CD40L mAb in combination with an anti-ICOSLG...
...TARGET/MARKER/PATHWAY: Chemokine CXC motif ligand 13 (CXCL13); CD40 ligand (CD40L; CD40LG; CD154); inducible T cell co-stimulator ligand (ICOSLG; B7-H2; B7RP1...

...in its Ig domain with ligands in the B7 family, such as PD-L1, VISTA and ICOSLG...
...Kenilworth, N.J. Targets DNAM-1 (CD226) ICOS - Inducible T cell co-stimulator ICOSLG (B7-H2; B7RP1) - Inducible T cell co-stimulator ligand...

...LSE:AZN; NYSE:AZN) MEDI0700 Lupus ICOSLG (B7-H2; B7RP1) - Inducible T cell co-stimulator ligand Bispecific mAb targeting BLyS (BAFF) and ICOSLG...

...soloMERs to the eye for ophthalmic autoimmune and inflammatory conditions. It has ELN/21 , an ICOSLG...
...tat protein HRAS - v-Ha-ras Harvey rat sarcoma viral oncogene homolog ICOSLG (B7-H2; B7RP1) - Inducible T cell co-stimulator ligand...

...several lineages of effector T cells, including Th1, Th2 and Th17. Engagement of ICOS by ICOSLG...

...in vitro screen identified B7-H2 as a ligand of CD28. In stimulated T cells, a B7-H2-blocking...
...T cell proliferation compared with a control antibody. Next steps include studying the role of B7-H2...

...in vitro screen identified B7-H2 as a ligand of CD28. In stimulated T cells, a B7-H2-blocking...
...T cell proliferation compared with a control antibody. Next steps include studying the role of B7-H2...