BioCentury | Oct 11, 2018
Distillery Therapeutics

Cancer

...INDICATION: Melanoma Patient sample and mouse studies suggest HAPLN1 could help treat metastatic melanoma. In 192...
...lymphatic tissue expression of HAPLN1 correlated with survival. In a mouse model of metastatic melanoma, HAPLN1...
...steps could include testing HAPLN1 in xenograft mouse models of metastatic melanoma. TARGET/MARKER/PATHWAY: Hyaluronan and proteoglycan link protein 1 (HAPLN1; LPP...
BioCentury | May 2, 2018
Distillery Techniques

Biomarkers

TECHNOLOGY: Gene profiling Tumor mutations of 22 genes could help diagnose prostate cancer, and mutations in two of them could help predict patient outcomes. Whole-genome sequencing of 112 primary and metastatic prostate cancer and matched...
BioCentury | Aug 18, 2016
Translation in Brief

Zip code for brain injury

Despite the fact that sports concussions and battlefield injuries have raised awareness about traumatic brain injury (TBI), there are still no therapies to treat the disease. A group from Sanford Burnham Prebys has reported in...
BioCentury | Sep 19, 2013
Distillery Therapeutics

Indication: Neurology

...Licensing status Publication and contact information Neurology Pain Hyaluronan and proteoglycan link protein 1 (HAPLN1; LPP) In vitro studies suggest LPP...
...degenerative disease. In 3D cultures of primary rabbit intervertebral disc cells, a human, 16-amino-acid, N-terminal LPP...
...the extracellular matrix proteins aggrecan and collagen II. Next steps include testing the potential of LPP...
BioCentury | Mar 27, 2008
Targets & Mechanisms

Celiac Attack

...inflammation ( SH2B3 , CCR3 , RGS-1 ) or cytoskeletal function ( TAGAP , LPP...
BioCentury | Sep 3, 2002
Company News

Alkermes other research news

...porous carriers of nanoparticles retain better flow and aerosolization properties of advantage large porous particle (LPP...
Items per page:
1 - 6 of 6