BioCentury | Oct 20, 2016
Distillery Therapeutics

Cancer

...B cell lymphoma Mouse studies suggest chimeric antigen receptor (CAR) T cells engineered to secrete HVEM...
...of B cell lymphoma, CD19 -targeting CAR T cells engineered to continuously produce a soluble HVEM...
...HVEM production. TARGET/MARKER/PATHWAY: Tumor necrosis factor receptor superfamily member 14 ( HVEM ; TNFRSF14 ; LIGHTR...
BioCentury | Oct 20, 2016
Distillery Therapeutics

Cancer

...B cell lymphoma Mouse studies suggest chimeric antigen receptor (CAR) T cells engineered to secrete HVEM...
...of B cell lymphoma, CD19 -targeting CAR T cells engineered to continuously produce a soluble HVEM...
...HVEM production. TARGET/MARKER/PATHWAY: Tumor necrosis factor receptor superfamily member 14 ( HVEM ; TNFRSF14 ; LIGHTR...
BioCentury | Oct 6, 2016
Product R&D

Local sensitivity

...Interleukin-10 IL-12 - Interleukin-12 BTLA - B and T lymphocyte attenuator HVEM ( TNFRSF14 ; LIGHTR...
...CAR) T cell line that continuously produces a therapeutic protein, capitalizing on its discovery of HVEM...
...T cells, allowing them to produce and secrete HVEM at the site of the tumors. HVEM...
BioCentury | Jul 14, 2016
Product R&D

Apogenix's hex on TNF

...to be influenced by our compounds." Starting with seven Apogenix has disclosed HERA agonists for HVEM...
...GITR ( TNFRSF18 ) - Glucocorticoid-induced tumor necrosis factor receptor-related protein HVEM ( TNFRSF14 ; LIGHTR...
BioCentury | Jul 14, 2016
Product R&D

Agonistic families

...GITR; TNFRSF18 ), tumor necrosis factor receptor superfamily member 14 ( HVEM ; TNFRSF14 ; LIGHTR...
BioCentury | Jan 30, 2014
Distillery Therapeutics

Indication: Autoimmune disease

...include targeting BTLA with its ligand, tumor necrosis factor receptor superfamily member 14 (HVEM; TNFRSF14; LIGHTR...
BioCentury | May 5, 2011
Cover Story

LIGHTs out for asthma

...and acts through tumor necrosis factor receptor superfamily member 14 ( TNFRSF14 ; LIGHTR ; HVEM...
...and the extracellular portion of Ltbr that inhibits Light's interactions with its receptors, Ltbr and Tnfrsf14...
BioCentury | Dec 4, 2008
Distillery Techniques

Technology: Drug delivery

...of the HSV surface glycoprotein D that was incapable of binding to viral entry receptors HVEM...
...in HER2-expressing SKOV3 human ovarian carcinoma cell lines but not in cell lines expressing only HVEM...
BioCentury | Jan 31, 2008
Distillery Therapeutics

This Week in Therapeutics

...suggest that preventing B and T lymphocyte attenuator (BTLA) from interacting with herpesvirus entry mediator (HVEM...
...Fusion of viral antigens to the C-terminal domain of HSV glycoprotein D (gD), which blocks HVEM-BTLA...
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