07:00 , Jul 14, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Homeobox C10 (HOXC10); cyclin dependent kinase 7 (CDK7)

Cancer INDICATION: Breast cancer Patient sample and cell culture studies suggest CDK7 inhibitors could help treat HOXC10-expressing, chemotherapy-resistant breast cancer. In breast cancer patients receiving chemotherapy, levels of HOXC10 mRNA were 10 times higher in...
07:00 , Apr 24, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Homeobox C10 (HOXC10) In vitro and mouse studies suggest decreasing HOXC10 methylation could help treat breast cancers resistant to aromatase inhibitors and other...