BC Innovations | Aug 29, 2019
Distillery Therapeutics

Cytomegalovirus vectors could form the backbone of an HIV vaccine

DISEASE CATEGORY: Infectious diseases INDICATION: HIV/AIDS An engineered cytomegalovirus vector-based vaccine protected against successive SIV infections in monkeys, suggesting it could be used to create an HIV vaccine. Monkeys vaccinated with an rhesus CMV (RhCMV)...
BC Week In Review | May 26, 2017
Clinical News

Inovio reports Phase I data for HIV vaccine Pennvax-GP

Inovio Pharmaceuticals Inc. (NASDAQ:INO) said data from the Phase I HVTN 098 trial in 94 healthy, HIV-uninfected volunteers showed that HIV vaccine Pennvax-GP produced "amongst the highest overall levels" of cellular and antibody immune response...
BC Extra | May 24, 2017
Clinical News

Inovio gains on HIV vaccine data

Inovio Pharmaceuticals Inc. (NASDAQ:INO) gained $1.55 (22%) to $8.68 on Wednesday after it said data from a Phase I study in healthy volunteers showed that HIV vaccine Pennvax-GP produced "amongst the highest overall levels" of...
BC Innovations | Jul 16, 2015
Distillery Therapeutics

Therapeutics: HIV env; HIV gag polyprotein; HIV pol; HIV gp140

Infectious disease INDICATION: HIV / AIDS Non-human primate studies identified a prime-boost vaccine protocol that could help prevent HIV infection. In a monkey model of SIV infection, two priming immunizations with an adenoviral vaccine encoding...
BC Innovations | Nov 14, 2013
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gag polyprotein; HIV p27 (nef); HIV pol; HIV env Macaque studies suggest mosaic HIV antigens delivered with a prime and boost vaccination...
BC Innovations | Mar 18, 2010
Cover Story

Creating a mosaic in HIV

U.S. researchers have shown that engineered, mosaic HIV vaccines could offer a better in vivo immune response to the virus than vaccines based on natural HIV epitopes. 1,2 The nearly universal mosaic vaccines trigger a...
BC Innovations | Mar 18, 2010
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gag; HIV p27 (nef); HIV pol; HIV env Two studies in macaques suggest that mosaic HIV antigens could help boost immune responses...
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