BioCentury | May 17, 2019
Product Development

Pushing China to the forefront: When a first-in-China regulatory strategy makes sense

...China MediTech Ltd. Immunomedics Inc. Roche Shenzhen Chipscreen Biosciences Ltd. c-Met receptor tyrosine kinase (c-MET) (MET) (HGFR) Histone deacetylase 1 (HDAC1) Histone deacetylase 10 (HDAC10) Histone...
BioCentury | Sep 5, 2013
Distillery Therapeutics

Indication: Cancer

...Publication and contact information Cancer Cervical cancer Histone deacetylase 10 (HDAC10) Patient tissue and mouse studies suggest increasing HDAC10...
...metastasis. In an analysis of clinical and microarray data in 60 cervical cancer samples, decreased HDAC10...
...a mouse xenograft model of human cervical cancer, HDAC10 overexpression decreased metastasis compared with normal HDAC10...
BioCentury | Aug 1, 2013
Distillery Therapeutics

Indication: Cancer

...status Publication and contact information Cancer Neuroendocrine tumors Histone deacetylase 10 (HDAC10) Computational and cell culture studies suggest HDAC10...
...patients with advanced-stage neuroblastoma, high HDAC10 expression correlated with poor overall survival. In neuroblastoma cells, HDAC10-targeting...
...small hairpin RNA increased doxorubicin-mediated cell death compared with control shRNA. Next steps include targeting HDAC10...
BioCentury | Apr 4, 2013
Cover Story

Closer to class IIa HDAC inhibitors

...HDAC4 , HDAC5 , HDAC7 and HDAC9 ) and class IIb ( HDAC6 and HDAC10...
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