BioCentury | Mar 29, 2019
Targets & Mechanisms

AACR moves in a myeloid direction

...non-responders Seres Therapeutics Inc. (NASDAQ:MCRB) 2839 High mobility group AT-hook 1 (HMGA1) Colorectal cancer Gut Mouse studies suggest inhibiting HMGA1... that shows a pathogenic gut microbiome bacteria induces expression of the chromatin remodeling protein HMGA1...
...receptor HER2 (EGFR2; ErbB2; Neu) - HLA-A2 - Major histocompatibility complex class I HMGA1 - High mobility group AT-hook 1...
BioCentury | May 26, 2016
Distillery Techniques

Techniques: Baculovirus-based vector system for transient, simultaneous expression of multiple genes for genome editing or cellular reprogramming

...CRISPR-associated protein 9 (Cas9) , a guide RNA and a construct encoding a high mobility group AT-hook 1 ( HMGA1...
BioCentury | Apr 22, 2010
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Ligase IV, DNA, ATP-dependent (LIG4); BTB domain containing 2 (BTBD2); high mobility group AT-hook 2 (HMGA2); regulator of telomere elongation helicase 1 (RTEL1);...
BioCentury | Jun 12, 2006
Company News

Oxis sales and marketing update

OXIS launched a series of reagents and antibodies to detect and measure high motility group A2 ( HMGA2 ) protein in tissue samples. HMGA2 is a marker for aggressive early stage breast cancer, OXIS said. Oxis International...
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